Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.53 |
| ▸ | ATR | Q13535 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | ROCK1 | Q13464 | 7/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 5/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.47 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.47 |
| ▸ | CLK2 | P49760 | 2/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.47 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.47 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.47 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.47 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.47 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.47 |
| ▸ | SGK2 | Q9HBY8 | 1/20 | 0.47 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25591775 | 0.92 | MAOB (0.62) | MAOBNPC1RAB9AROCK1MAP4K4 | |
| SCHEMBL25590490 | 0.88 | ATR (0.58) | MAOBATRNPC1RAB9AROCK1 | |
| SCHEMBL25591603 | 0.85 | ATR (0.57) | MAOBATRNPC1RAB9AROCK1 | |
| SCHEMBL25590563 | 0.83 | SMN1; SMN2 (0.45) | MAOBNPC1RAB9AROCK1ROCK2 | |
| SCHEMBL25591688 | 0.81 | KDR (0.45) | MAOBNPC1RAB9ACSNK2A1ALDH1A1 | |
| SCHEMBL25590486 | 0.80 | RAB9A (0.53) | NPC1RAB9AKDM4EMEN1ALDH1A1 | |
| SCHEMBL25590481 | 0.80 | SMN1; SMN2 (0.47) | MAOBATRNPC1RAB9AMEN1 | |
| SCHEMBL15887002 | 0.77 | MAOB (0.81) | MAOBNPC1RAB9AROCK1ROCK2 | |
| SCHEMBL30184009 | 0.77 | KDM4E (0.55) | ATRNPC1RAB9AROCK1ROCK2 | |
| SCHEMBL25590402 | 0.77 | KDM4E (0.55) | ATRNPC1RAB9AROCK1ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023088435-A1 | PREPARATION FOR TRISUBSTITUTED PYRIDINE DERIVATIVE AND APPLICATION AS AROMATIC HYDROCARBON RECEPTOR MODULATOR | 成都奥睿药业有限公司 | 2023-05-25 | — | — | WO | disclosed |