Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 2/20 | 0.45 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.45 |
| ▸ | TEK | Q02763 | 2/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | KIT | P10721 | 1/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.45 |
| ▸ | FLT1 | P17948 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | QPCT | Q16769 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25590495 | 0.88 | RAB9A (0.55) | RAB9ANPC1SMN1; SMN2POLBHTT | |
| SCHEMBL25591687 | 0.85 | MAPT (0.62) | RAB9ANPC1SMN1; SMN2POLBHTT | |
| SCHEMBL25591775 | 0.82 | MAOB (0.62) | RAB9ANPC1SMN1; SMN2PDGFRBKMT2A | |
| SCHEMBL25591688 | 0.81 | KDR (0.45) | RAB9ANPC1SMN1; SMN2POLBKDR | |
| SCHEMBL25590666 | 0.80 | MAOB (0.53) | RAB9ANPC1KMT2AMAPTMEN1 | |
| SCHEMBL25590669 | 0.79 | TP53 (0.44) | RAB9ANPC1SMN1; SMN2POLBTEK | |
| SCHEMBL25590481 | 0.78 | SMN1; SMN2 (0.47) | RAB9ANPC1SMN1; SMN2POLBHTT | |
| SCHEMBL25590563 | 0.77 | SMN1; SMN2 (0.45) | RAB9ANPC1SMN1; SMN2POLBHTT | |
| SCHEMBL25590671 | 0.76 | SMN1; SMN2 (0.46) | RAB9ANPC1SMN1; SMN2POLBHTT | |
| SCHEMBL25590497 | 0.75 | LRRK2 (0.45) | RAB9ANPC1SMN1; SMN2POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023088435-A1 | PREPARATION FOR TRISUBSTITUTED PYRIDINE DERIVATIVE AND APPLICATION AS AROMATIC HYDROCARBON RECEPTOR MODULATOR | 成都奥睿药业有限公司 | 2023-05-25 | — | — | WO | disclosed |