Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.46 |
| ▸ | CES1 | P23141 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8338715 | 1.00 | CES2 (0.46) | CES2CES1TSHRMAPK1L3MBTL1 | |
| SCHEMBL2559260 | 1.00 | CES2 (0.46) | CES2CES1TSHRMAPK1L3MBTL1 | |
| SCHEMBL17074011 | 0.80 | CES2 (0.44) | CES2CES1CA1CA2ALDH1A1 | |
| SCHEMBL6708832 | 0.80 | ALDH1A1 (0.45) | CES2CES1ATMGSK3BSRD5A2 | |
| SCHEMBL2559234 | 0.80 | CES2 (0.44) | CES2CES1MAPK1CA1CA2 | |
| SCHEMBL23275556 | 0.80 | TPMT (0.43) | CA1CA2GSK3B | |
| SCHEMBL23285683 | 0.80 | TPMT (0.43) | CA1CA2GSK3B | |
| SCHEMBL12489982 | 0.80 | CES2 (0.44) | CES2CES1CA1CA2ALDH1A1 | |
| SCHEMBL2559233 | 0.80 | CES2 (0.44) | CES2CES1MAPK1CA1CA2 | |
| SCHEMBL2559511 | 0.80 | CES2 (0.44) | CES2CES1MAPK1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0323625-B1 | Process for preparing 3-[2-chloro-2(4-chlorophenyl)-vinyl]-2,2-dimethyl-cyclopropane carboxylic acid | BAYER AG (DE) | 1992-09-09 | — | — | EP | claimed |
| US-4897505-A | Process for the preparation of 3-(2-chloro-2-(4-chloro-phenyl)-vinyl)-2,2-dimethylcyclopropanecarboxylic acid | BAYER AKTIENGESELLSCHAFT (DE) | 1990-01-30 | — | — | US | claimed |
| EP-0323625-A2 | Process for preparing 3-[2-chloro-2(4-chlorophenyl)-vinyl]-2,2-dimethyl-cyclopropane carboxylic acid | BAYER AG (DE) | 1989-07-12 | — | — | EP | claimed |
| JP-1203350-A | — | — | None | — | — | JP | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |
| EP-2558577-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011127933-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2011-10-20 | — | — | WO | disclosed |
| US-4992577-A | Preparation of 3-vinyl-substituted 2,2-dimethylcyclopropane-1-carboxylic acids and esters and intermediates therefor | BAYER AKTIENGESELLSCHAFT (DE) | 1991-02-12 | — | — | US | disclosed |
| US-4897505-A | Process for the preparation of 3-(2-chloro-2-(4-chloro-phenyl)-vinyl)-2,2-dimethylcyclopropanecarboxylic acid | BAYER AKTIENGESELLSCHAFT (DE) | 1990-01-30 | — | — | US | disclosed |
| US-4897505-A | Process for the preparation of 3-(2-chloro-2-(4-chloro-phenyl)-vinyl)-2,2-dimethylcyclopropanecarboxylic acid | BAYER AKTIENGESELLSCHAFT (DE) | 1990-01-30 | — | — | US | disclosed |
| JP-H01203350-A | PREPARATION OF 3-(2-CHLORO-2-(4-CHLOROPHENYL)-VINYL)-2,2-DIMETHYLCYCLOPROPANECARBOXYLIC ACID | BAYER AG | 1989-08-16 | — | — | JP | disclosed |
| EP-0323625-A2 | Process for preparing 3-[2-chloro-2(4-chlorophenyl)-vinyl]-2,2-dimethyl-cyclopropane carboxylic acid | BAYER AG (DE) | 1989-07-12 | — | — | EP | disclosed |
| EP-0323625-A2 | Process for preparing 3-[2-chloro-2(4-chlorophenyl)-vinyl]-2,2-dimethyl-cyclopropane carboxylic acid | BAYER AG (DE) | 1989-07-12 | — | — | EP | disclosed |
| EP-0095047-B1 | PROCESS FOR THE PREPARATION OF 3-VINYL-SUBSTITUTED 2,2-DIMETHYL-CYCLOPROPANE-1-CARBOXYLIC ACIDS OR THEIR ESTERS, AND INTERMEDIATE PRODUCTS THEREFOR | BAYER AG (DE) | 1985-11-27 | — | — | EP | disclosed |
| EP-0095047-A1 | Process for the preparation of 3-vinyl-substituted 2,2-dimethyl-cyclopropane-1-carboxylic acids or their esters, and intermediate products therefor | BAYER AG (DE) | 1983-11-30 | — | — | EP | disclosed |
| EP-0019089-A1 | 5-Aryl-3-(1'-halogen-1'-methyl)ethyl-pent-4-en-carboxylic acid esters, process for their preparation, and their use for the preparation of 3-(2-arylvinyl)-2,2-dimethyl-cyclopropane-1-carboxylic acid esters | BAYER AG (DE) | 1980-11-26 | — | — | EP | disclosed |