Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 17/20 | 0.63 |
| ▸ | CDK12 | Q9NYV4 | 17/20 | 0.63 |
| ▸ | CCNT1 | O60563 | 13/20 | 0.63 |
| ▸ | CCNE1 | P24864 | 13/20 | 0.63 |
| ▸ | CDK2 | P24941 | 13/20 | 0.63 |
| ▸ | CDK9 | P50750 | 13/20 | 0.63 |
| ▸ | CDK7 | P50613 | 11/20 | 0.51 |
| ▸ | CCNH | P51946 | 11/20 | 0.51 |
| ▸ | MNAT1 | P51948 | 10/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30439353 | 1.00 | CCNK (0.63) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL30261023 | 0.89 | CCNK (0.60) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL25273499 | 0.89 | CCNK (0.60) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL25600387 | 0.86 | CCNK (0.62) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL30204044 | 0.86 | CCNK (0.62) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL21629046 | 0.81 | CCNK (0.44) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL30554768 | 0.81 | CCNK (0.44) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL25595070 | 0.80 | CCNK (0.47) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL30957590 | 0.80 | TDO2 (0.47) | CCNKCDK12CCNT1CCNE1CDK2 | |
| SCHEMBL24900493 | 0.80 | TDO2 (0.47) | CCNKCDK12CCNT1CCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240360165-A1 | INHIBITORS OF CYCLIN DEPENDENT KINASE 7 (CDK7) | MEDIC LIFE SCIENCES, INC. | 2024-10-31 | — | — | US | disclosed |
| EP-4295852-A2 | PIPERIDINE DERIVATIVES AS INHIBITORS OF CYCLIN DEPENDENT KINASE 7 (CDK7) | Syros Pharmaceuticals, Inc. (US) | 2023-12-27 | — | — | EP | disclosed |
| EP-3484871-B1 | PIPERIDINE DERIVATIVES AS INHIBITORS OF CYCLIN DEPENDENT KINASE 7 (CDK7) | SYROS PHARMACEUTICALS INC (US) | 2023-06-07 | — | — | EP | disclosed |
| EP-3484871-B1 | PIPERIDINE DERIVATIVES AS INHIBITORS OF CYCLIN DEPENDENT KINASE 7 (CDK7) | SYROS PHARMACEUTICALS INC (US) | 2023-06-07 | — | — | EP | disclosed |
| US-20230062491-A1 | INHIBITORS OF CYCLIN DEPENDENT KINASE 7 (CDK7) | MEDIC LIFE SCIENCES, INC. | 2023-03-02 | — | — | US | disclosed |
| CN-110036004-A | Inhibitors of cyclin dependent kinase 7(CDK7) | 希洛斯医药品股份有限公司 | 2019-07-19 | — | — | CN | disclosed |
| EP-3484871-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | Syros Pharmaceuticals, Inc. (US) | 2019-05-22 | — | — | EP | disclosed |
| WO-2018013867-A1 | INHIBITORS OF CYCLIN DEPENDNT KINASE 7 (CDK7) | MARINEAU JASON J (US) | 2018-01-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240360165-A1 | INHIBITORS OF CYCLIN DEPENDENT KINASE 7 (CDK7) | CDK7, CDK3, CDK9 | CCNK 11/4885CDK12 28/4885CCNT1 32/4885 |
| US-20230062491-A1 | INHIBITORS OF CYCLIN DEPENDENT KINASE 7 (CDK7) | CDK7, CDK3, CDK9 | CCNK 11/4885CDK12 28/4885CCNT1 32/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.