SCHEMBL25595129

SCHEMBL25595129

Cc1noc2c3c(ccc12)CC1(C3)CN(CC2CCNCC2)C1

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM2B Q8NHM5 1/20 0.35
HRH1 P35367 1/20 0.30
DRD3 P35462 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25600646 0.80 HRH1 (0.44) KDM2BHRH1DRD3
SCHEMBL25600216 0.79 HRH1 (0.40) KDM2BHRH1DRD3
SCHEMBL25817343 0.77 HRH1 (0.31) HRH1DRD3
SCHEMBL25592007 0.74 CYP11B1 (0.30)
SCHEMBL25600319 0.73 KDM2B (0.31) KDM2BHRH1DRD3
SCHEMBL25600648 0.71 SSTR4 (0.32)
SCHEMBL25595253 0.71
SCHEMBL25595528 0.69 BCHE (0.32)
SCHEMBL25595529 0.69 KHK (0.34) HRH1DRD3
SCHEMBL25600320 0.68 HRH1 (0.45) KDM2BHRH1DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023088406-A1 FUSED IMIDE DERIVATIVE 正大天晴药业集团股份有限公司 2023-05-25 WO disclosed