SCHEMBL25817343

SCHEMBL25817343

Cc1noc2c3c(ccc12)CC1(CNC1)C3

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HRH1 P35367 1/20 0.31
DRD3 P35462 1/20 0.31
KCNA3 P22001 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9910138 0.61 MCL1 (0.39) KCNA3
SCHEMBL24482375 0.59 ADRA2A (0.41) DRD3
SCHEMBL21788503 0.59 HTR2C (0.40)
SCHEMBL12946499 0.57 CYP2A6 (0.42) KCNA3
SCHEMBL8404486 0.57 SMN1; SMN2 (0.53) KCNA3
SCHEMBL10216188 0.57 KCNA3 (0.36) KCNA3
SCHEMBL17307560 0.56 IMPDH2 (0.33) KCNA3
SCHEMBL7606859 0.56 ALDH1A1 (0.46) KCNA3
SCHEMBL21326866 0.55 DRD2 (0.40) DRD3
SCHEMBL24481731 0.55 ADRA2A (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023125944-A1 COMPOUND CONTAINING HETEROCYCLIC RING 正大天晴药业集团股份有限公司 2023-07-06 WO disclosed