SCHEMBL25596197

SCHEMBL25596197

Cc1ccc(C(O)C(N)(CF)C(=O)O)cc1

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.41
CYP2C19 P33261 1/20 0.36
ACHE P22303 1/20 0.36
ALOX5 P09917 1/20 0.36
KIF11 P52732 4/20 0.35
CNR1 P21554 1/20 0.35
CNR2 P34972 1/20 0.35
ALDH1A1 P00352 3/20 0.34
FFAR1 O14842 1/20 0.34
AKR1C3 P42330 1/20 0.34
AKR1C2 P52895 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
STAT3 P40763 1/20 0.33
KEAP1 Q14145 1/20 0.33
NFE2L2 Q16236 1/20 0.33
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22077893 0.85 BLM (0.40) LMNAALDH1A1
SCHEMBL6720239 0.85 LMNA (0.40) LMNASMN1; SMN2
SCHEMBL13268126 0.72 CYP3A4 (0.36) LMNACYP2C19ACHEALDH1A1SMN1; SMN2
SCHEMBL22074748 0.71 BLM (0.42) LMNACYP2C19
SCHEMBL22074749 0.71 BLM (0.42) LMNACYP2C19
SCHEMBL11096673 0.71 BLM (0.42) LMNACYP2C19
SCHEMBL23646629 0.70 LMNA (0.42) LMNACYP2C19ACHEALOX5CNR1
SCHEMBL13502434 0.69 AKR1C3 (0.40) LMNAALOX5KIF11ALDH1A1AKR1C3
SCHEMBL22074701 0.69 ESR1 (0.41) LMNASMN1; SMN2
SCHEMBL13502438 0.69 AKR1C3 (0.40) LMNAALOX5KIF11ALDH1A1AKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230181493-A1 BIOMARKERS RELATED TO PARKINSON'S DISEASE AND METHODS OF USING THE SAME SENDA BIOSCIENCES INC (US) 2023-06-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230181493-A1 BIOMARKERS RELATED TO PARKINSON'S DISEASE AND METHODS OF USING THE SAME COMT, SNCA, PARK7 LMNA 4451/4885CYP2C19 3233/4885ACHE 14/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.