Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 13/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.59 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | FYN | P06241 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8601473 | 0.84 | ESR1 (0.63) | ESR1ESR2PDE10ATDP1KDM4E | |
| SCHEMBL14478205 | 0.84 | ALOX15 (0.66) | ESR1TDP1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL25596190 | 0.82 | ESR1 (0.52) | ESR1ESR2PDE10ATDP1KDM4E | |
| SCHEMBL5511404 | 0.82 | SLC6A2 (0.52) | ESR1ESR2TDP1KDM4EALDH1A1 | |
| SCHEMBL6338791 | 0.81 | TDP1 (0.77) | ESR1ESR2PDE10ATDP1KDM4E | |
| SCHEMBL2486290 | 0.81 | TDP1 (0.77) | ESR1ESR2PDE10ATDP1KDM4E | |
| SCHEMBL6716878 | 0.81 | TDP1 (0.58) | ESR1ESR2PDE10ATDP1KDM4E | |
| SCHEMBL10608436 | 0.81 | TDP1 (0.77) | ESR1ESR2PDE10ATDP1KDM4E | |
| Hydrochloric Acid SCHEMBL1578093 | 0.80 | TDP1 (0.74) | ESR1ESR2PDE10ATDP1KDM4E | |
| SCHEMBL8585296 | 0.79 | SLC6A2 (0.46) | ESR1ESR2KDM4EALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230181493-A1 | BIOMARKERS RELATED TO PARKINSON'S DISEASE AND METHODS OF USING THE SAME | SENDA BIOSCIENCES INC (US) | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230181493-A1 | BIOMARKERS RELATED TO PARKINSON'S DISEASE AND METHODS OF USING THE SAME | COMT, SNCA, PARK7 | ESR1 4421/4885ESR2 4494/4885PDE10A 1028/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.