Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 1/20 | 0.38 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.38 |
| ▸ | ITGAL | P20701 | 1/20 | 0.38 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CRHBP | P24387 | 2/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | USP1 | O94782 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27936039 | 0.83 | ITGB2 (0.38) | ITGB2ICAM1ITGALMAP3K14SSTR4 | |
| SCHEMBL97554 | 0.77 | ITGB2 (0.41) | ITGB2ICAM1ITGALMAP3K14SSTR4 | |
| SCHEMBL130895 | 0.74 | ITGB2 (0.41) | ITGB2ICAM1ITGALMAP3K14SSTR4 | |
| SCHEMBL6005414 | 0.71 | ITGB2 (0.46) | ITGB2ICAM1ITGALMAP3K14SSTR4 | |
| SCHEMBL12727583 | 0.71 | ITGB2 (0.46) | ITGB2ICAM1ITGALMAP3K14SSTR4 | |
| SCHEMBL2616050 | 0.71 | ITGB2 (0.46) | ITGB2ICAM1ITGALMAP3K14SSTR4 | |
| SCHEMBL30388151 | 0.71 | ITGB2 (0.46) | ITGB2ICAM1ITGALMAP3K14SSTR4 | |
| SCHEMBL3716706 | 0.71 | ITGB2 (0.46) | ITGB2ICAM1ITGALMAP3K14SSTR4 | |
| SCHEMBL13117930 | 0.71 | ITGB2 (0.46) | ITGB2ICAM1ITGALMAP3K14SSTR4 | |
| SCHEMBL6677076 | 0.70 | KDM4E (0.43) | ITGB2ICAM1ITGALMAP3K14SSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023102747-A1 | ANTIMALARIAL AGENTS | MERCK SHARP & DOHME LLC (US) | 2023-06-15 | — | — | WO | disclosed |