Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 1/20 | 0.46 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.46 |
| ▸ | ITGAL | P20701 | 1/20 | 0.46 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CRHBP | P24387 | 2/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12727583 | 1.00 | ITGB2 (0.46) | ITGB2ICAM1ITGALMAP3K14LMNA | |
| SCHEMBL13117930 | 1.00 | ITGB2 (0.46) | ITGB2ICAM1ITGALMAP3K14LMNA | |
| SCHEMBL2616050 | 1.00 | ITGB2 (0.46) | ITGB2ICAM1ITGALMAP3K14LMNA | |
| SCHEMBL19494124 | 0.88 | ITGB2 (0.43) | ITGB2ICAM1ITGALMAP3K14LMNA | |
| SCHEMBL16224873 | 0.88 | ITGB2 (0.43) | ITGB2ICAM1ITGALMAP3K14LMNA | |
| SCHEMBL17086645 | 0.88 | ITGB2 (0.43) | ITGB2ICAM1ITGALMAP3K14LMNA | |
| SCHEMBL691833 | 0.78 | LTB4R (0.43) | ITGB2ICAM1ITGALABCG2 | |
| SCHEMBL18570198 | 0.78 | LTB4R (0.43) | ITGB2ICAM1ITGALABCG2 | |
| SCHEMBL13117931 | 0.78 | LTB4R (0.43) | ITGB2ICAM1ITGALABCG2 | |
| SCHEMBL10820255 | 0.78 | LTB4R (0.43) | ITGB2ICAM1ITGALABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230149414-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2023-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230149414-A1 | COMPOUNDS AND USES THEREOF | VHL, CLN6, TFEB | ITGB2 1609/4885ICAM1 4818/4885ITGAL 3404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.