Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 1/20 | 0.41 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.41 |
| ▸ | ITGAL | P20701 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CRHBP | P24387 | 2/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8588712 | 0.81 | LTB4R (0.40) | ITGB2ICAM1ITGAL | |
| SCHEMBL25596609 | 0.77 | ITGB2 (0.38) | ITGB2ICAM1ITGALSMN1; SMN2LMNA | |
| SCHEMBL27936039 | 0.77 | ITGB2 (0.38) | ITGB2ICAM1ITGALSMN1; SMN2LMNA | |
| SCHEMBL6677076 | 0.77 | KDM4E (0.43) | ITGB2ICAM1ITGALSMN1; SMN2SSTR4 | |
| SCHEMBL10233941 | 0.76 | KDM4E (0.41) | SMN1; SMN2LMNAMAP3K14GAA | |
| SCHEMBL29222608 | 0.76 | MAP3K14 (0.47) | MAP3K14 | |
| SCHEMBL27262601 | 0.76 | FABP6 (0.39) | TRPV1 | |
| SCHEMBL29222597 | 0.76 | ADRA2A (0.47) | LMNAHTT | |
| SCHEMBL27676537 | 0.76 | GAA (0.41) | SMN1; SMN2LMNAMAP3K14GAA | |
| SCHEMBL27465075 | 0.76 | MAOA (0.41) | SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114853707-B | Method for synthesizing difluoro hydrogen methylation 2, 3-dihydro benzopyran-4-ketone derivative | 上饶师范学院 | 2024-01-26 | — | — | CN | claimed |
| CN-114853707-A | Method for synthesizing difluoro-hydrogen methylated 2, 3-dihydrobenzopyran-4-ketone derivative | 上饶师范学院 | 2022-08-05 | — | — | CN | claimed |
| CN-112898260-A | 3-carbonyl-2H-benzopyran compound or pharmaceutically acceptable salt thereof, preparation method and application | 中国药科大学 | 2021-06-04 | — | — | CN | claimed |
| EP-0540690-A1 | PHOTOCHROMIC CHROMENE COMPOUNDS. | PPG INDUSTRIES INC (US) | 1993-05-12 | — | — | EP | claimed |
| EP-0540690-A4 | PHOTOCHROMIC CHROMENE COMPOUNDS. | PPG INDUSTRIES INC (US) | 1993-02-12 | — | — | EP | claimed |
| WO-1992001959-A1 | PHOTOCHROMIC CHROMENE COMPOUNDS | PPG INDUSTRIES, INC. (US) | 1992-02-06 | — | — | WO | claimed |
| EP-0157267-B1 | SUBSTITUTED BENZOPYRANS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN MEDICINES | BAYER AG (DE) | 1988-11-23 | — | — | EP | claimed |
| EP-0114374-B1 | SUBSTITUTED 4-AMINOMETHYLENE CHROMANS OR CHROMENES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN MEDICINES | BAYER AG (DE) | 1986-07-23 | — | — | EP | claimed |
| EP-0157267-A2 | Substituted benzopyrans, process for their preparation and their use in medicines | BAYER AG (DE) | 1985-10-09 | — | — | EP | claimed |
| EP-0114374-A1 | Substituted 4-aminomethylene chromans or chromenes, process for their preparation and their use in medicines | BAYER AG (DE) | 1984-08-01 | — | — | EP | claimed |
| CN-114853707-B | Method for synthesizing difluoro hydrogen methylation 2, 3-dihydro benzopyran-4-ketone derivative | 上饶师范学院 | 2024-01-26 | — | — | CN | disclosed |
| CN-114853707-B | Method for synthesizing difluoro hydrogen methylation 2, 3-dihydro benzopyran-4-ketone derivative | 上饶师范学院 | 2024-01-26 | — | — | CN | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| CN-115215808-A | Compositions and methods for treating cancer | 加利福尼亚大学董事会 | 2022-10-21 | — | — | CN | disclosed |
| CN-114920638-A | Cyclohexane-1, 3, 5-triyltris ((2-hydroxyphenyl) ketone) compounds and synthetic method thereof | 湖南大学 | 2022-08-19 | — | — | CN | disclosed |
| US-4659737-A | Substituted aminomethyl benzopyrans having anti-hypertensive activities | BAYER AKTIENGESELLSCHAFT (DE) | 1987-04-21 | — | — | US | disclosed |
| EP-0114374-B1 | SUBSTITUTED 4-AMINOMETHYLENE CHROMANS OR CHROMENES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN MEDICINES | BAYER AG (DE) | 1986-07-23 | — | — | EP | disclosed |
| US-4563458-A | CIRCULATORY SYSTEM DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 1986-01-07 | — | — | US | disclosed |
| EP-0157267-A2 | Substituted benzopyrans, process for their preparation and their use in medicines | BAYER AG (DE) | 1985-10-09 | — | — | EP | disclosed |
| EP-0114374-A1 | Substituted 4-aminomethylene chromans or chromenes, process for their preparation and their use in medicines | BAYER AG (DE) | 1984-08-01 | — | — | EP | disclosed |