Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16164709 | 0.88 | L3MBTL1 (0.55) | GAAMAPTALDH1A1HTTMAPK1 | |
| SCHEMBL27756462 | 0.87 | MAPT (0.47) | MAPTALDH1A1HTTMAPK1L3MBTL1 | |
| SCHEMBL25221087 | 0.84 | DPP4 (0.43) | GAAMAPTALDH1A1HTTL3MBTL1 | |
| SCHEMBL25269885 | 0.84 | DPP4 (0.43) | GAAMAPTALDH1A1HTTL3MBTL1 | |
| SCHEMBL30533985 | 0.84 | DPP4 (0.43) | GAAMAPTALDH1A1HTTL3MBTL1 | |
| SCHEMBL29190649 | 0.81 | HRH4 (0.44) | MAPTALDH1A1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL30833658 | 0.81 | HRH4 (0.44) | MAPTALDH1A1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL19795220 | 0.80 | DDB1 (0.45) | GAAALDH1A1HTTL3MBTL1PKM | |
| SCHEMBL25220005 | 0.79 | PPARA (0.43) | GAAMAPTALDH1A1HTTL3MBTL1 | |
| SCHEMBL25273114 | 0.79 | PPARA (0.43) | GAAMAPTALDH1A1HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023102184-A1 | BICYCLIC AMINE COMPOUNDS AS CDK12 INHIBITORS | INCYTE CORPORATION (US) | 2023-06-08 | — | — | WO | disclosed |