Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | RHOA | P61586 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29190649 | 1.00 | HRH4 (0.44) | HRH4HRH3KMT2AMEN1SIRT6 | |
| SCHEMBL25598317 | 0.81 | GAA (0.48) | HRH4HRH3KMT2AMEN1L3MBTL1 | |
| SCHEMBL30833752 | 0.80 | MEN1 (0.41) | HRH4HRH3KMT2AMEN1SIRT6 | |
| SCHEMBL29190644 | 0.80 | MEN1 (0.41) | HRH4HRH3KMT2AMEN1SIRT6 | |
| SCHEMBL27756462 | 0.79 | MAPT (0.47) | KMT2AMEN1L3MBTL1ALDH1A1POLB | |
| SCHEMBL25269885 | 0.76 | DPP4 (0.43) | L3MBTL1ALDH1A1MAPTSMN1; SMN2KCNH2 | |
| SCHEMBL25221087 | 0.76 | DPP4 (0.43) | L3MBTL1ALDH1A1MAPTSMN1; SMN2KCNH2 | |
| SCHEMBL30533985 | 0.76 | DPP4 (0.43) | L3MBTL1ALDH1A1MAPTSMN1; SMN2KCNH2 | |
| SCHEMBL4191910 | 0.75 | SIRT6 (0.72) | KMT2AMEN1SIRT6L3MBTL1ALDH1A1 | |
| SCHEMBL328462 | 0.75 | WDR5 (0.49) | KMT2AMEN1SIRT6ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896744-B | Selective EGFR inhibitor | 成都先导药物开发股份有限公司 | 2024-04-16 | — | — | CN | disclosed |