Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F13A1 | P00488 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | TGM1 | P22735 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | TEC | P42680 | 1/20 | 0.39 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25681675 | 0.93 | SMN1; SMN2 (0.42) | SMN1; SMN2GLALMNAHTTMAPT | |
| SCHEMBL25599144 | 0.87 | MAPT (0.45) | SMN1; SMN2GLALMNAHTTMAPT | |
| SCHEMBL25598176 | 0.87 | SMN1; SMN2 (0.54) | TGM2SMN1; SMN2GLALMNAHTT | |
| SCHEMBL25599220 | 0.82 | UCHL3 (0.39) | F13A1TGM2TGM1EGFR | |
| SCHEMBL25681648 | 0.81 | SMN1; SMN2 (0.41) | TGM2SMN1; SMN2GLALMNAHTT | |
| SCHEMBL25599129 | 0.81 | SMN1; SMN2 (0.43) | SMN1; SMN2GLALMNAHTTMAPT | |
| SCHEMBL25599089 | 0.79 | SMN1; SMN2 (0.43) | SMN1; SMN2GLALMNAHTTMAPT | |
| SCHEMBL25681606 | 0.79 | SMN1; SMN2 (0.43) | SMN1; SMN2GLALMNAHTTMAPT | |
| SCHEMBL25270317 | 0.78 | CCNK (0.42) | F13A1TGM2TGM1SMN1; SMN2LMNA | |
| SCHEMBL30464349 | 0.78 | CCNK (0.42) | F13A1TGM2TGM1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023102184-A1 | BICYCLIC AMINE COMPOUNDS AS CDK12 INHIBITORS | INCYTE CORPORATION (US) | 2023-06-08 | — | — | WO | disclosed |