Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12296593 | 0.83 | KMT2A (0.54) | PKMALDH1A1POLBHTTKMT2A | |
| SCHEMBL1919732 | 0.82 | KMT2A (0.53) | PKMALDH1A1POLBHTTKMT2A | |
| SCHEMBL16980490 | 0.77 | KMT2A (0.51) | PKMALDH1A1POLBHTTKMT2A | |
| SCHEMBL29040725 | 0.76 | PKM (0.58) | PKMALDH1A1POLBHTTKMT2A | |
| SCHEMBL9217072 | 0.76 | KMT2A (0.47) | PKMALDH1A1POLBHTTKMT2A | |
| SCHEMBL16984270 | 0.74 | ACHE (0.48) | PKMALDH1A1POLBHTTKMT2A | |
| SCHEMBL436674 | 0.73 | PKM (0.89) | PKMALDH1A1POLBHTTKMT2A | |
| SCHEMBL20154516 | 0.73 | KMT2A (0.50) | PKMALDH1A1POLBHTTKMT2A | |
| SCHEMBL7407681 | 0.73 | CYP2C19 (0.56) | PKMALDH1A1POLBHTTKMT2A | |
| SCHEMBL18221902 | 0.73 | CYP2C19 (0.53) | PKMALDH1A1POLBHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484871-B1 | PIPERIDINE DERIVATIVES AS INHIBITORS OF CYCLIN DEPENDENT KINASE 7 (CDK7) | SYROS PHARMACEUTICALS INC (US) | 2023-06-07 | — | — | EP | disclosed |