Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | PAK4 | O96013 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.37 |
| ▸ | CLK2 | P49760 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | CDK7 | P50613 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
| ▸ | PRKX | P51817 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19864847 | 1.00 | CA12 (0.41) | CA12CA9SMN1; SMN2NPSR1CDC7 | |
| SCHEMBL5022149 | 0.90 | ALDH1A1 (0.41) | SMN1; SMN2MAOAEPHX1ALDH1A1 | |
| SCHEMBL24658467 | 0.84 | MAOA (0.38) | SMN1; SMN2NPSR1MAOAHTTALDH1A1 | |
| SCHEMBL18629569 | 0.80 | NPSR1 (0.56) | SMN1; SMN2NPSR1EPHX1HPGDKMT2A | |
| SCHEMBL11573903 | 0.79 | CA12 (0.40) | CA12CA9SMN1; SMN2NPSR1EPHX1 | |
| SCHEMBL31481620 | 0.79 | CA12 (0.40) | CA12CA9SMN1; SMN2NPSR1EPHX1 | |
| SCHEMBL19675983 | 0.79 | BTK (0.43) | CA12CA9SMN1; SMN2NPSR1MAOA | |
| SCHEMBL9029685 | 0.79 | EPHX1 (0.48) | SMN1; SMN2MAOAEPHX1ALDH1A1 | |
| SCHEMBL9027748 | 0.79 | EPHX1 (0.48) | SMN1; SMN2MAOAEPHX1ALDH1A1 | |
| SCHEMBL9027751 | 0.79 | EPHX1 (0.48) | SMN1; SMN2MAOAEPHX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4198031-A1 | TLR7/8 ANTAGONISTS AND USES THEREOF | Merck Patent GmbH (DE) | 2023-06-21 | — | — | EP | disclosed |