Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2561466 | 0.85 | ALDH1A1 (0.42) | HTTALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL29955555 | 0.84 | ALDH1A3 (0.53) | ALDH1A3HTTALDH1A1SMN1; SMN2GAA | |
| SCHEMBL2557689 | 0.83 | ALDH1A1 (0.58) | ALDH1A3HTTALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL15333466 | 0.82 | ALDH1A3 (0.50) | ALDH1A3HTTALDH1A1SMN1; SMN2GAA | |
| SCHEMBL2557395 | 0.81 | ALDH1A3 (0.49) | ALDH1A3HTTALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL2563059 | 0.81 | ALDH1A3 (0.49) | ALDH1A3HTTALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL15330511 | 0.80 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2HPGDPOLBTDP1 | |
| SCHEMBL2555033 | 0.80 | ALDH1A1 (0.49) | HTTALDH1A1SMN1; SMN2HPGDPOLB | |
| SCHEMBL11400879 | 0.80 | MAPT (0.50) | HTTALDH1A1PKMSMN1; SMN2RAB9A | |
| SCHEMBL2561807 | 0.80 | HPGD (0.52) | ALDH1A3HTTALDH1A1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |
| EP-2558577-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011127933-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2011-10-20 | — | — | WO | disclosed |