Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.34 |
| ▸ | CNR1 | P21554 | 5/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25595530 | 0.87 | HRH1 (0.36) | HRH1DRD3HRH3CYP2D6 | |
| SCHEMBL25600320 | 0.77 | HRH1 (0.45) | HRH1DRD3HRH3KCNH2CYP2D6 | |
| SCHEMBL25600644 | 0.76 | HRH1 (0.39) | HRH1DRD3HRH3 | |
| SCHEMBL25595529 | 0.76 | KHK (0.34) | HRH1DRD3 | |
| SCHEMBL25597203 | 0.74 | DRD3 (0.49) | HRH1DRD3CYP2D6 | |
| SCHEMBL25597315 | 0.74 | HRH1 (0.39) | HRH1DRD3 | |
| SCHEMBL25817345 | 0.70 | HRH1 (0.45) | HRH1DRD3HRH3 | |
| SCHEMBL25823774 | 0.69 | HCRTR1 (0.35) | HRH1DRD3 | |
| SCHEMBL25595351 | 0.69 | HRH1 (0.32) | HRH1DRD3 | |
| SCHEMBL25602212 | 0.69 | HRH1 (0.40) | HRH1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023088406-A1 | FUSED IMIDE DERIVATIVE | 正大天晴药业集团股份有限公司 | 2023-05-25 | — | — | WO | disclosed |