Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CCND3 | P30281 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | SMO | Q99835 | 1/20 | 0.31 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25593050 | 0.83 | HRH1 (0.46) | HRH1DRD3HRH3 | |
| SCHEMBL25600413 | 0.76 | HRH1 (0.36) | HRH1DRD3HRH3 | |
| SCHEMBL25595530 | 0.75 | HRH1 (0.36) | HRH1DRD3KMT2AHRH3 | |
| SCHEMBL25592128 | 0.74 | DRD3 (0.43) | HRH1DRD3 | |
| SCHEMBL25595529 | 0.73 | KHK (0.34) | HRH1DRD3KMT2A | |
| SCHEMBL25600216 | 0.72 | HRH1 (0.40) | HRH1DRD3HRH3 | |
| SCHEMBL25597203 | 0.71 | DRD3 (0.49) | HRH1DRD3 | |
| SCHEMBL25600320 | 0.70 | HRH1 (0.45) | HRH1DRD3HRH3 | |
| SCHEMBL25817345 | 0.68 | HRH1 (0.45) | HRH1DRD3HRH3 | |
| SCHEMBL25602212 | 0.66 | HRH1 (0.40) | HRH1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023088406-A1 | FUSED IMIDE DERIVATIVE | 正大天晴药业集团股份有限公司 | 2023-05-25 | — | — | WO | disclosed |