SCHEMBL2560163

SCHEMBL2560163

Cc1cccc(NC(=O)CN2CCCC(C=O)C2)c1

nearest known ligand 0.64

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.64
DRD4 P21917 12/20 0.59
DRD2 P14416 5/20 0.59
DRD3 P35462 4/20 0.59
KDM4E B2RXH2 1/20 0.53
LMNA P02545 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15330243 0.87 MEN1 (0.52) ALDH1A1KDM4E
SCHEMBL2556253 0.87 EPHX2 (0.54) ALDH1A1DRD4DRD2DRD3KDM4E
SCHEMBL2559118 0.87 KCNT1 (0.53) ALDH1A1DRD4KDM4ELMNA
SCHEMBL2557020 0.86 ALDH1A1 (0.74) ALDH1A1DRD4DRD2DRD3
SCHEMBL15330891 0.86 ALDH1A1 (0.63) ALDH1A1KDM4ELMNA
SCHEMBL17896859 0.82 ALDH1A1 (0.89) ALDH1A1DRD4DRD2DRD3
SCHEMBL2560196 0.80 MEN1 (0.57) ALDH1A1KDM4ELMNA
SCHEMBL2562333 0.79 MAPT (0.53) ALDH1A1KDM4ELMNA
SCHEMBL2559211 0.79 ALDH1A1 (0.65) ALDH1A1DRD4KDM4ELMNA
SCHEMBL4003239 0.78 DRD4 (0.80) ALDH1A1DRD4DRD2DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
US-11225655-B2 Bi-functional complexes and methods for making and using such complexes NUEVOLUTION A/S (DK) 2022-01-18 US disclosed
EP-3540059-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES Nuevolution A/S (DK) 2019-09-18 EP disclosed
EP-2558577-B1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION AS (DK) 2018-12-12 EP disclosed
US-20130281324-A1 BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2013-10-24 US disclosed
EP-2558577-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES Nuevolution A/S (DK) 2013-02-20 EP disclosed
WO-2011127933-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2011-10-20 WO disclosed