Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2559211 | 0.89 | ALDH1A1 (0.65) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL2562333 | 0.89 | MAPT (0.53) | MEN1KMT2APOLBALDH1A1NPC1 | |
| SCHEMBL15330891 | 0.89 | ALDH1A1 (0.63) | MEN1KMT2APOLBALDH1A1NPC1 | |
| SCHEMBL2560163 | 0.87 | ALDH1A1 (0.64) | ALDH1A1KDM4E | |
| SCHEMBL2561342 | 0.84 | ALDH1A1 (0.60) | MEN1KMT2ATSHRPOLBALDH1A1 | |
| SCHEMBL2560196 | 0.82 | MEN1 (0.57) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL2559118 | 0.80 | KCNT1 (0.53) | MEN1KMT2ATSHRPOLBALDH1A1 | |
| SCHEMBL2556253 | 0.80 | EPHX2 (0.54) | MEN1KMT2APOLBALDH1A1KCNT1 | |
| SCHEMBL10210776 | 0.79 | NPC1 (0.74) | MEN1KMT2ATSHRPOLBALDH1A1 | |
| SCHEMBL2558206 | 0.78 | L3MBTL1 (0.41) | MEN1KMT2APOLBALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |