SCHEMBL25601932

SCHEMBL25601932

C[N+](C)(C)CCOC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.59
SCN1A P35498 2/20 0.48
SCN2A Q99250 2/20 0.48
SCN3A Q9NY46 2/20 0.48
CHRM2 P08172 2/20 0.43
CHRM4 P08173 2/20 0.43
CHRM1 P11229 2/20 0.43
CHRM3 P20309 2/20 0.43
CHRNB4 P30926 1/20 0.43
CHRNA3 P32297 1/20 0.43
CHRNA7 P36544 1/20 0.43
CHRNA10 Q9GZZ6 1/20 0.43
CHRNA9 Q9UGM1 1/20 0.43
HRH4 Q9H3N8 1/20 0.41
TK2 O00142 6/20 0.40
DUT P33316 1/20 0.40
TK1 P04183 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11275984 0.82 KIF11 (0.74) KIF11HRH4TK2DUTTK1
SCHEMBL2348691 0.80 KIF11 (0.65) KIF11CHRM2CHRM1CHRM3HRH4
SCHEMBL25601968 0.79 SLC6A11 (0.41)
SCHEMBL27859727 0.78 SMN1; SMN2 (0.39) KIF11SCN1ASCN2ASCN3ACHRM2
SCHEMBL17297687 0.77 KIF11 (0.61) KIF11CHRM3HRH4TK2DUT
SCHEMBL26176905 0.76 KIF11 (0.65) KIF11HRH4TK2DUTTK1
SCHEMBL26176899 0.76 KIF11 (0.65) KIF11HRH4TK2DUTTK1
SCHEMBL31430932 0.76 KIF11 (0.65) KIF11HRH4TK2DUTTK1
SCHEMBL26176887 0.76 KIF11 (0.65) KIF11HRH4TK2DUTTK1
SCHEMBL26176885 0.76 KIF11 (0.65) KIF11HRH4TK2DUTTK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107893078-A Target siRNA, expression vector and virion and its pharmacy application of synaptotagmin 11 西安交通大学 2018-04-10 CN claimed
WO-2023107161-A1 BREAKABLE EMULSIFIERS HALLIBURTON ENERGY SERVICES, INC. (US) 2023-06-15 WO disclosed
US-20230174841-A1 Breakable Emulsifiers HALLIBURTON ENERGY SERVICES, INC. (US) 2023-06-08 US disclosed
CN-105980398-B The mutant fragments of OspA and its correlation technique and purposes 瓦尔尼瓦奥地利有限责任公司 2019-11-26 CN disclosed
CN-107602676-A OspA mutant fragments and its correlation technique and purposes 瓦尔尼瓦奥地利有限责任公司 2018-01-19 CN disclosed
CN-104487084-B Mutant fragments of OspA and methods and uses related thereto 瓦尔尼瓦奥地利有限责任公司 2017-09-22 CN disclosed
CN-106459933-A Method for increasing grain yield 佛罗里达大学研究基金公司 2017-02-22 CN disclosed
CN-105980398-A Mutant fragments of OspA and methods and uses relating thereto 瓦尔尼瓦奥地利有限责任公司 2016-09-28 CN disclosed