Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 2/20 | 0.74 |
| ▸ | CYBB | P04839 | 1/20 | 0.70 |
| ▸ | CA12 | O43570 | 2/20 | 0.67 |
| ▸ | CA1 | P00915 | 2/20 | 0.67 |
| ▸ | CA2 | P00918 | 2/20 | 0.67 |
| ▸ | CA9 | Q16790 | 2/20 | 0.67 |
| ▸ | HPN | P05981 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | GAPDH | P04406 | 1/20 | 0.60 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.60 |
| ▸ | HSPA8 | P11142 | 1/20 | 0.60 |
| ▸ | CD44 | P16070 | 1/20 | 0.60 |
| ▸ | MSN | P26038 | 1/20 | 0.60 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.60 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.60 |
| ▸ | NR4A1 | P22736 | 3/20 | 0.56 |
| ▸ | KLK3 | P07288 | 1/20 | 0.54 |
| ▸ | AR | P10275 | 1/20 | 0.54 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25602306 | 0.92 | CYBB (0.70) | USP7CYBBCA12CA1CA2 | |
| SCHEMBL16406028 | 0.85 | USP7 (1.00) | USP7CYBBCA12CA1CA2 | |
| SCHEMBL25602299 | 0.85 | USP7 (0.72) | USP7CYBBCA12CA1CA2 | |
| SCHEMBL25602301 | 0.83 | USP7 (0.80) | USP7CYBBCA12CA1CA2 | |
| SCHEMBL25602307 | 0.83 | USP7 (0.87) | USP7CYBBCA12CA1CA2 | |
| SCHEMBL31277265 | 0.82 | CYBB (1.00) | USP7CYBBCA12CA1CA2 | |
| SCHEMBL15213475 | 0.82 | CYBB (1.00) | USP7CYBBCA12CA1CA2 | |
| SCHEMBL13186614 | 0.79 | ESR1 (0.67) | CA12CA1CA2CA9MAPT | |
| SCHEMBL16406027 | 0.79 | CYBB (0.84) | USP7CYBBHPNMAPTTP53 | |
| SCHEMBL2031914 | 0.79 | HPN (1.00) | USP7CYBBCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11672794-B2 | Therapeutic targeting of the BAP1 complex in cancer | NORTHWESTERN UNIVERSITY (US) | 2023-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11672794-B2 | Therapeutic targeting of the BAP1 complex in cancer | BAP1, MCL1, STUB1 | USP7 113/4885CYBB 1940/4885CA12 2092/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.