SCHEMBL2560375

SCHEMBL2560375

O=Cc1nnc2n1CCNC2

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 1/20 0.31
GSK3B P49841 1/20 0.30
DYRK1A Q13627 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20157173 0.75
SCHEMBL2559739 0.73 GSK3B (0.43) GSK3BDYRK1A
SCHEMBL24656037 0.71 GSK3B (0.32) MGLLGSK3BDYRK1A
SCHEMBL109874 0.71 MGLL (0.33) MGLLGSK3BDYRK1A
SCHEMBL17611615 0.71 MGLL (0.33) MGLLGSK3BDYRK1A
SCHEMBL929279 0.71 POLB (0.47) MGLLGSK3BDYRK1A
SCHEMBL5935866 0.70 MGLL (0.43) MGLLGSK3BDYRK1A
SCHEMBL2555237 0.70 XDH (0.35) GSK3BDYRK1A
Hydrochloric Acid SCHEMBL9932011 0.69 MGLL (0.32) MGLLGSK3BDYRK1A
Hydrochloric Acid SCHEMBL15385166 0.69 POLB (0.46) MGLLGSK3BDYRK1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
US-11225655-B2 Bi-functional complexes and methods for making and using such complexes NUEVOLUTION A/S (DK) 2022-01-18 US disclosed
EP-3540059-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES Nuevolution A/S (DK) 2019-09-18 EP disclosed
EP-2558577-B1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION AS (DK) 2018-12-12 EP disclosed
US-20130281324-A1 BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2013-10-24 US disclosed
EP-2558577-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES Nuevolution A/S (DK) 2013-02-20 EP disclosed
WO-2011127933-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2011-10-20 WO disclosed