Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | THRB | P10828 | 3/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 5/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25604141 | 0.87 | MAPT (0.46) | HDAC1NR1H2MAPTESR2LMNA | |
| SCHEMBL25825902 | 0.81 | L3MBTL1 (0.39) | L3MBTL1HDAC1NR1H2ESR2LMNA | |
| SCHEMBL25604199 | 0.75 | ESR2 (0.43) | L3MBTL1HDAC1NR1H2MAPTESR2 | |
| SCHEMBL25604356 | 0.73 | ESR2 (0.39) | L3MBTL1NR1H2ESR2LMNATHRB | |
| SCHEMBL24302902 | 0.72 | SMN1; SMN2 (0.43) | MAPTLMNATP53POLBSMN1; SMN2 | |
| SCHEMBL24302316 | 0.72 | CA12 (0.46) | HDAC1MAPTLMNATP53POLB | |
| SCHEMBL24754283 | 0.72 | CA12 (0.51) | HDAC1MAPTLMNATP53POLB | |
| SCHEMBL23117302 | 0.71 | KDM4E (0.47) | MAPTESR2LMNAPOLBSMN1; SMN2 | |
| SCHEMBL27036991 | 0.71 | AKR1C3 (0.50) | HDAC1NR1H2MAPTESR2LMNA | |
| SCHEMBL23640266 | 0.70 | MAPT (0.46) | L3MBTL1MAPTLMNATP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125944-A1 | COMPOUND CONTAINING HETEROCYCLIC RING | 正大天晴药业集团股份有限公司 | 2023-07-06 | — | — | WO | disclosed |
| WO-2023088406-A1 | FUSED IMIDE DERIVATIVE | 正大天晴药业集团股份有限公司 | 2023-05-25 | — | — | WO | disclosed |