Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25604199 | 0.94 | ESR2 (0.43) | ESR2NR1H2L3MBTL1ADORA1JAK2 | |
| SCHEMBL25604354 | 0.88 | SMN1; SMN2 (0.42) | ESR2NR1H2ADORA1JAK2GPR119 | |
| SCHEMBL25825902 | 0.87 | L3MBTL1 (0.39) | ESR2NR1H2L3MBTL1ADORA1GPR119 | |
| SCHEMBL25825841 | 0.83 | L3MBTL1 (0.37) | L3MBTL1JAK2GPR119SMN1; SMN2LMNA | |
| SCHEMBL25604262 | 0.82 | ESR2 (0.46) | ESR2NR1H2ADORA1SMN1; SMN2 | |
| SCHEMBL25604198 | 0.82 | ESR2 (0.46) | ESR2NR1H2ADORA1SMN1; SMN2 | |
| SCHEMBL25826024 | 0.80 | L3MBTL1 (0.37) | L3MBTL1GPR119SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL25604265 | 0.80 | L3MBTL1 (0.37) | L3MBTL1GPR119SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL31323712 | 0.76 | CYP11B2 (0.47) | L3MBTL1GPR119SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL29324509 | 0.75 | TLR8 (0.42) | L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125944-A1 | COMPOUND CONTAINING HETEROCYCLIC RING | 正大天晴药业集团股份有限公司 | 2023-07-06 | — | — | WO | disclosed |
| WO-2023088406-A1 | FUSED IMIDE DERIVATIVE | 正大天晴药业集团股份有限公司 | 2023-05-25 | — | — | WO | disclosed |