Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 11/20 | 0.62 |
| ▸ | LCK | P06239 | 8/20 | 0.62 |
| ▸ | JAK3 | P52333 | 13/20 | 0.61 |
| ▸ | JAK2 | O60674 | 1/20 | 0.57 |
| ▸ | SYK | P43405 | 2/20 | 0.54 |
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18884637 | 0.93 | BTK (0.64) | BTKLCKJAK3SYKEGFR | |
| SCHEMBL25604902 | 0.89 | BTK (0.60) | BTKLCKJAK3EGFR | |
| SCHEMBL25604897 | 0.89 | BTK (0.60) | BTKLCKJAK3SYKEGFR | |
| SCHEMBL18884550 | 0.88 | JAK3 (0.62) | BTKLCKJAK3SYK | |
| SCHEMBL18884512 | 0.87 | JAK3 (0.72) | BTKLCKJAK3EGFR | |
| SCHEMBL25606965 | 0.87 | JAK3 (0.67) | BTKLCKJAK3EGFR | |
| SCHEMBL18884623 | 0.87 | BTK (0.61) | BTKLCKJAK3SYKEGFR | |
| SCHEMBL21855202 | 0.87 | BTK (0.59) | BTKLCKJAK3SYKEGFR | |
| SCHEMBL21946319 | 0.87 | BTK (0.59) | BTKLCKJAK3SYKEGFR | |
| SCHEMBL18296155 | 0.87 | LCK (0.73) | BTKLCKJAK3SYKEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023088406-A1 | FUSED IMIDE DERIVATIVE | 正大天晴药业集团股份有限公司 | 2023-05-25 | — | — | WO | disclosed |