Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.66 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.65 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.59 |
| ▸ | APP | P05067 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | AGXT | P21549 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22874 | 0.94 | ENPP2 (0.70) | MAOBENPP2MRGPRX4APPTP53 | |
| SCHEMBL15331009 | 0.91 | ENPP2 (0.74) | MAOBENPP2MRGPRX4TP53PKM | |
| SCHEMBL23719 | 0.88 | ENPP2 (0.65) | MAOBENPP2MRGPRX4APPRAB9A | |
| SCHEMBL22563 | 0.86 | ENPP2 (0.67) | MAOBENPP2APPRAB9A | |
| SCHEMBL15332207 | 0.86 | MAOB (0.67) | MAOBENPP2MRGPRX4APPRAB9A | |
| SCHEMBL2555516 | 0.85 | ENPP2 (0.59) | MAOBENPP2MRGPRX4SMN1; SMN2 | |
| SCHEMBL16687432 | 0.85 | ENPP2 (0.59) | MAOBENPP2 | |
| SCHEMBL29138052 | 0.84 | ENPP2 (0.65) | MAOBENPP2MRGPRX4TP53PKM | |
| SCHEMBL30688670 | 0.84 | ENPP2 (0.65) | MAOBENPP2MRGPRX4TP53PKM | |
| SCHEMBL15330536 | 0.82 | NR4A2 (0.56) | MAOBENPP2PKMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |
| EP-2558577-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011127933-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2011-10-20 | — | — | WO | disclosed |