Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 4/20 | 0.65 |
| ▸ | F10 | P00742 | 1/20 | 0.54 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.50 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30688670 | 1.00 | ENPP2 (0.65) | ENPP2F10CYP4F2CYP4A11LMNA | |
| SCHEMBL22315 | 0.90 | CYP4F2 (0.58) | ENPP2CYP4F2CYP4A11NR4A2MAOB | |
| SCHEMBL15331009 | 0.87 | ENPP2 (0.74) | ENPP2LMNAMAOBTP53PKM | |
| SCHEMBL16687434 | 0.85 | ENPP2 (0.68) | ENPP2FFAR1MAOBTP53PKM | |
| SCHEMBL2561245 | 0.85 | ENPP2 (0.64) | ENPP2MAOBRAB9ASMN1; SMN2MRGPRX4 | |
| SCHEMBL2555516 | 0.84 | ENPP2 (0.59) | ENPP2CYP4F2CYP4A11MAOBSMN1; SMN2 | |
| SCHEMBL2555065 | 0.84 | ENPP2 (0.71) | ENPP2MAOBTP53PKMNFKB1 | |
| SCHEMBL16687432 | 0.84 | ENPP2 (0.59) | ENPP2FFAR1MAOB | |
| SCHEMBL15330536 | 0.84 | NR4A2 (0.56) | ENPP2CYP1A2CYP2C19NR4A2MAOB | |
| SCHEMBL31051000 | 0.84 | NR4A2 (0.56) | ENPP2CYP1A2CYP2C19NR4A2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117343081-A | MAT2A inhibitor, pharmaceutical composition and application thereof | 南京正大天晴制药有限公司 | 2024-01-05 | — | — | CN | disclosed |