Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITK | Q08881 | 10/20 | 0.55 |
| ▸ | TTK | P33981 | 5/20 | 0.53 |
| ▸ | AURKB | Q96GD4 | 4/20 | 0.53 |
| ▸ | INCENP | Q9NQS7 | 4/20 | 0.53 |
| ▸ | AURKA | O14965 | 3/20 | 0.53 |
| ▸ | TNKS | O95271 | 1/20 | 0.51 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.51 |
| ▸ | KIT | P10721 | 3/20 | 0.50 |
| ▸ | SRC | P12931 | 3/20 | 0.50 |
| ▸ | FLT3 | P36888 | 3/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.50 |
| ▸ | GPR142 | Q7Z601 | 4/20 | 0.47 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10062818 | 0.88 | ITK (0.66) | ITKTTKAURKBINCENPAURKA | |
| SCHEMBL10062875 | 0.86 | ITK (0.62) | ITKTTKAURKBINCENPAURKA | |
| SCHEMBL16941895 | 0.80 | PRKCZ (0.53) | ITKTTKAURKBINCENPAURKA | |
| SCHEMBL25606285 | 0.79 | TTK (0.62) | ITKTTKAURKBINCENPAURKA | |
| Hydrochloric Acid SCHEMBL16929551 | 0.79 | PRKCZ (0.52) | ITKTTKAURKBINCENPAURKA | |
| Hydrochloric Acid SCHEMBL16929552 | 0.79 | PRKCZ (0.52) | ITKTTKAURKBINCENPAURKA | |
| SCHEMBL1552756 | 0.76 | ULK1 (0.56) | TNKSTNKS2ROCK2PBK | |
| SCHEMBL16941891 | 0.75 | ITK (0.47) | ITKTTKAURKBINCENPAURKA | |
| SCHEMBL11456925 | 0.74 | ITK (0.73) | ITKTTKAURKBINCENPAURKA | |
| SCHEMBL11450045 | 0.73 | ITK (0.68) | ITKTTKAURKBINCENPAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107714-A2 | METHODS FOR TREATING NEUROLOGICAL DISORDERS | PROTHENA BIOSCIENCES LIMITED (IE) | 2023-06-15 | — | — | WO | disclosed |