SCHEMBL2560729

SCHEMBL2560729

CC(C)(C)COc1ccc(N)cc1

nearest known ligand 0.58

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 5/20 0.58
TSHR P16473 2/20 0.58
RAB9A P51151 4/20 0.47
MAPT P10636 3/20 0.47
ALDH1A1 P00352 3/20 0.47
NPC1 O15118 3/20 0.47
MAPK1 P28482 2/20 0.47
HPGD P15428 1/20 0.47
XDH P47989 1/20 0.46
MAOB P27338 5/20 0.45
GAA P10253 1/20 0.45
MAOA P21397 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
CYP3A4 P08684 2/20 0.44
NUDT1 P36639 1/20 0.44
NFE2L2 Q16236 1/20 0.43
APP P05067 2/20 0.42
TEAD4 Q15561 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13141341 0.88 NQO1 (0.48) TDP1TSHRMAPTALDH1A1HPGD
SCHEMBL661780 0.86 TDP1 (0.58) TDP1TSHRRAB9AMAPTALDH1A1
Hydrochloric Acid SCHEMBL8639741 0.84 TDP1 (0.56) TDP1TSHRRAB9AMAPTALDH1A1
SCHEMBL22445082 0.84 TDP1 (0.56) TDP1TSHRRAB9AMAPTALDH1A1
SCHEMBL777299 0.84 TDP1 (0.56) TDP1TSHRRAB9AMAPTALDH1A1
Hydrochloric Acid SCHEMBL2960337 0.83 TDP1 (0.54) TDP1TSHRRAB9AMAPTALDH1A1
SCHEMBL12012132 0.83 TDP1 (0.54) TDP1TSHRRAB9AMAPTALDH1A1
Hydrochloric Acid SCHEMBL775512 0.83 TDP1 (0.54) TDP1TSHRRAB9AMAPTALDH1A1
SCHEMBL2348583 0.83 TDP1 (0.54) TDP1TSHRRAB9AMAPTALDH1A1
SCHEMBL25165364 0.82 TDP1 (0.50) TDP1TSHRRAB9AMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115362535-A UV curable resin composition suitable for redistribution layers 设计分子有限公司 2022-11-18 CN claimed
EP-3856510-A1 HIGH-TEMPERATURE POLYMER AEROGEL COMPOSITES Aerogel Technologies, LLC (US) 2021-08-04 EP claimed
CN-112955313-A High temperature polymer aerogel composites 气凝胶科技有限责任公司 2021-06-11 CN claimed
CN-109651631-B Polyimide film with low dielectric loss 深圳瑞华泰薄膜科技股份有限公司 2020-09-25 CN claimed
CN-111386299-A Low color polymers for use in electronic devices E.I.内穆尔杜邦公司 2020-07-07 CN claimed
CN-111108144-A Curable polyimide 设计分子有限公司 2020-05-05 CN claimed
WO-2020069023-A1 HIGH-TEMPERATURE POLYMER AEROGEL COMPOSITES AEROGEL TECHNOLOGIES, LLC (US) 2020-04-02 WO claimed
CN-118318000-A Crosslinkable thermoplastic 株式会社钟化 2024-07-09 CN disclosed
CN-118108944-A Thermosetting imide resin composition, and uncured resin film, cured resin film, prepreg, substrate, and adhesive using same 信越化学工业株式会社 2024-05-31 CN disclosed
CN-112739747-B Polymer for use in electronic devices 杜邦电子公司 2024-05-14 CN disclosed
CN-117946519-A Curable resin composition, temporary fixing material, and method for producing electronic component 积水化学工业株式会社 2024-04-30 CN disclosed
CN-117946520-A Curable resin composition, temporary fixing material, and method for producing electronic component 积水化学工业株式会社 2024-04-30 CN disclosed
CN-112424204-B Polymer for use in electronic devices 杜邦电子公司 2024-04-30 CN disclosed
US-20030008868-A1 Compounds useful as anti-inflammatory agents BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) 2003-01-09 US disclosed
WO-2002092576-A1 DIARYLUREA DERIVATIVES USEFUL AS ANTI-INFLAMMATORY AGENTS BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) 2002-11-21 WO disclosed
EP-0663417-B1 POLYIMIDE LAMINATE COMPRISING THERMOPLASTIC POLYIMIDE POLYMER OR THERMOPLASTIC POLYIMIDE FILM, AND PROCESS FOR PRODUCING THE LAMINATE KANEGAFUCHI CHEMICAL IND (JP) 2000-03-29 EP disclosed
US-5621068-A Thermoplastic polyimide polymer; thermoplastic polyimide film; polyimide laminate; and method of manufacturing the laminate KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1997-04-15 US disclosed
EP-0663417-A1 THERMOPLASTIC POLYIMIDE POLYMER, THERMOPLASTIC POLYIMIDE FILM, POLYIMIDE LAMINATE, AND PROCESS FOR PRODUCING THE LAMINATE KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1995-07-19 EP disclosed
US-5360671-A Heat, solvent, oxidative stability THE UNIVERSITY OF AKRON (US) 1994-11-01 US disclosed
EP-0273242-A2 2-Pyri(mi)dylthio-aryl ether BAYER AG (DE) 1988-07-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030008868-A1 Compounds useful as anti-inflammatory agents TNF, MPO, PTGES TDP1 3045/4885TSHR 4755/4885RAB9A 2471/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.