Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLRMT | O00411 | 1/20 | 0.34 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.33 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24312545 | 0.94 | POLRMT (0.33) | POLRMTTMPRSS2DOT1LRIPK1 | |
| SCHEMBL24917203 | 0.93 | POLRMT (0.32) | POLRMTTMPRSS2DOT1L | |
| SCHEMBL24312549 | 0.89 | POLRMT (0.35) | POLRMTTMPRSS2DOT1LRIPK1 | |
| SCHEMBL24790439 | 0.89 | RNASEL (0.35) | POLRMTTMPRSS2 | |
| SCHEMBL26317024 | 0.89 | POLRMT (0.33) | POLRMTTMPRSS2DOT1LRIPK1 | |
| SCHEMBL24313023 | 0.89 | POLRMT (0.33) | POLRMTTMPRSS2DOT1LRIPK1 | |
| SCHEMBL24791043 | 0.88 | POLRMT (0.33) | POLRMTTMPRSS2DOT1LRIPK1 | |
| SCHEMBL26213567 | 0.88 | POLRMT (0.34) | POLRMTTMPRSS2DOT1L | |
| SCHEMBL24791044 | 0.88 | POLRMT (0.33) | POLRMTTMPRSS2DOT1LRIPK1 | |
| SCHEMBL24917062 | 0.88 | POLRMT (0.34) | POLRMTTMPRSS2DOT1LRIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023102472-A1 | ANTIVIRAL PRODRUGS AND FORMULATIONS THEREOF | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-06-08 | — | — | WO | disclosed |