Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 3/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DRD1 | P21728 | 2/20 | 0.35 |
| ▸ | DRD5 | P21918 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ME2 | P23368 | 3/20 | 0.34 |
| ▸ | ME1 | P48163 | 3/20 | 0.34 |
| ▸ | ME3 | Q16798 | 3/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8281445 | 0.74 | HRH4 (0.46) | AOC3HTR3ADRD2DRD1DRD5 | |
| SCHEMBL6222902 | 0.73 | AOC3 (0.46) | AOC3HTR3ADRD2DRD1DRD5 | |
| SCHEMBL2759552 | 0.71 | HRH4 (0.49) | HTR3ADRD2DRD1DRD5DRD3 | |
| SCHEMBL26972357 | 0.70 | RET (0.37) | DRD2DRD1DRD5DRD3HTR1A | |
| SCHEMBL21673537 | 0.70 | AOC3 (0.35) | AOC3DRD2DRD1DRD5DRD3 | |
| SCHEMBL12675278 | 0.70 | HTR3A (0.47) | AOC3HTR3ADRD2DRD1DRD5 | |
| SCHEMBL19003513 | 0.70 | HTR3A (0.47) | HTR3ADRD2DRD1DRD5DRD3 | |
| SCHEMBL11988947 | 0.70 | SMO (0.52) | AOC3HTR3ADRD2DRD1DRD5 | |
| SCHEMBL5122324 | 0.70 | HTR3A (0.47) | HTR3ADRD2DRD1DRD5DRD3 | |
| SCHEMBL25156908 | 0.69 | HTR3A (0.44) | AOC3HTR3ADRD2DRD1DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023096987-A1 | BRM TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2023-06-01 | — | — | WO | disclosed |