Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | PARP10 | Q53GL7 | 8/20 | 0.51 |
| ▸ | PARP1 | P09874 | 6/20 | 0.51 |
| ▸ | F7 | P08709 | 1/20 | 0.47 |
| ▸ | F3 | P13726 | 1/20 | 0.47 |
| ▸ | PARP11 | Q9NR21 | 3/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.37 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2611066 | 0.90 | PARP10 (0.63) | HPGDGFERHSD17B10PARP10PARP1 | |
| SCHEMBL25795405 | 0.88 | PARP11 (0.51) | HPGDGFERHSD17B10PARP10PARP1 | |
| SCHEMBL24170587 | 0.85 | PARP10 (0.47) | HPGDGFERHSD17B10PARP10PARP1 | |
| SCHEMBL8163994 | 0.80 | HPGD (0.58) | HPGDGFERHSD17B10PARP10PARP1 | |
| SCHEMBL15830755 | 0.79 | PARP10 (0.81) | GFERPARP10PARP1F7F3 | |
| SCHEMBL279822 | 0.78 | PARP10 (0.63) | PARP10PARP1F7F3PARP11 | |
| SCHEMBL14849265 | 0.77 | HPGD (0.46) | HPGDGFERHSD17B10LMNAKDM4E | |
| SCHEMBL1401942 | 0.77 | MAOA (0.48) | HPGDGFERHSD17B10LMNAKDM4E | |
| SCHEMBL9910073 | 0.77 | GFER (0.44) | HPGDGFERHSD17B10LMNAKDM4E | |
| SCHEMBL10201434 | 0.76 | PARP1 (0.56) | PARP10PARP1F7F3PARP11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159446-A1 | Methods and Compositions for Targeting Tregs using CCR8 Inhibitors | NANJING IMMUNOPHAGE BIOMEDICAL CO., LTD. (CN) | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159446-A1 | Methods and Compositions for Targeting Tregs using CCR8 Inhibitors | CCR8, CCR1, CCR3 | HPGD 2003/4885GFER 4509/4885HSD17B10 2773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.