Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP11 | Q9NR21 | 9/20 | 0.51 |
| ▸ | PARP10 | Q53GL7 | 9/20 | 0.51 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 6/20 | 0.41 |
| ▸ | PARP1 | P09874 | 2/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL279822 | 0.90 | PARP10 (0.63) | PARP11PARP10GRM5PARP1PDPK1 | |
| SCHEMBL25609113 | 0.88 | HPGD (0.52) | PARP11PARP10GSK3BHPGDGFER | |
| SCHEMBL279725 | 0.80 | CLK4 (0.49) | PARP11PARP10GSK3BHPGDGFER | |
| SCHEMBL25124516 | 0.79 | PARP11 (0.49) | PARP11PARP10GSK3BGFERGRM5 | |
| SCHEMBL12090727 | 0.79 | PARP10 (0.81) | PARP11PARP10GSK3BGFERGRM5 | |
| SCHEMBL2611066 | 0.78 | PARP10 (0.63) | PARP11PARP10HPGDGFERHSD17B10 | |
| SCHEMBL12376488 | 0.77 | MAOA (0.56) | HSD17B10GRM5 | |
| SCHEMBL6421470 | 0.77 | MAPT (0.50) | HPGDGFERHSD17B10 | |
| SCHEMBL1888691 | 0.76 | PARP10 (0.60) | PARP11PARP10GSK3BGRM5PARP1 | |
| SCHEMBL23160447 | 0.76 | PARP10 (0.60) | PARP11PARP10GSK3BGRM5PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109912-A1 | 3, 4-DIHYDROISOQUINOLIN-1 (2H) -ONES DERIVATIVES AS STING ANTAGONISTS AND THE USE THEREOF | BEIGENE, LTD. (KY) | 2023-06-22 | — | — | WO | disclosed |