SCHEMBL25609262

SCHEMBL25609262

c1ccc(-c2cccc(-c3nc(-c4ccccc4)nc(-c4nc(-c5ccccc5)nc(-c5ccccc5-c5ccc6ccc7ccc8nn(-c9ccccc9)nc8c7c6c5)n4)n3)c2)cc1

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.35
ABCG2 Q9UNQ0 1/20 0.34
GRM5 P41594 2/20 0.33
PARP1 P09874 1/20 0.32
MET P08581 1/20 0.31
KDM4E B2RXH2 2/20 0.31
MEN1 O00255 1/20 0.31
NPC1 O15118 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
STAT1 P42224 1/20 0.31
RAB9A P51151 1/20 0.31
KMT2A Q03164 1/20 0.31
NT5E P21589 1/20 0.31
HPGD P15428 1/20 0.31
MAPK10 P53779 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25548278 0.99 ALOX5 (0.35) ALOX5ABCG2GRM5PARP1MET
SCHEMBL25548283 0.96 ABCG2 (0.38) ALOX5ABCG2GRM5PARP1MET
SCHEMBL25609264 0.96 ALOX5 (0.37) ALOX5ABCG2GRM5PARP1MET
SCHEMBL25548277 0.95 ALOX5 (0.38) ALOX5ABCG2GRM5PARP1MET
SCHEMBL25609263 0.94 ABCG2 (0.40) ALOX5ABCG2GRM5PARP1KDM4E
SCHEMBL25548270 0.94 ALOX5 (0.39) ALOX5ABCG2GRM5PARP1MET
SCHEMBL25548276 0.93 ABCG2 (0.40) ALOX5ABCG2GRM5PARP1KDM4E
SCHEMBL25548141 0.93 ALOX5 (0.39) ALOX5PARP1METKDM4EMEN1
SCHEMBL25548281 0.93 ALOX5 (0.39) ALOX5PARP1METKDM4EMEN1
SCHEMBL25548286 0.93 ALOX5 (0.39) ALOX5PARP1METKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230167089-A1 ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) 2023-06-01 US disclosed
US-20230167089-A1 ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) 2023-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230167089-A1 ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF PIEZO1, VCL, VDAC3 ALOX5 977/4885ABCG2 739/4885GRM5 1758/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.