Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.61 |
| ▸ | HTR2C | P28335 | 1/20 | 0.61 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | MPO | P05164 | 2/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 9/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.51 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.51 |
| ▸ | BCHE | P06276 | 4/20 | 0.51 |
| ▸ | ACHE | P22303 | 4/20 | 0.51 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.51 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27752893 | 0.86 | HTR2A (0.60) | HTR2AHTR2CALOX5PTGS2GAA | |
| SCHEMBL27737431 | 0.83 | CHRM2 (0.63) | HTR2AHTR2CMPOCHRM2GRIN1 | |
| SCHEMBL29207914 | 0.83 | HTR2A (0.57) | HTR2AHTR2CGAAALDH1A1MPO | |
| SCHEMBL8138468 | 0.83 | CHRM2 (0.72) | GAAALDH1A1CHRM2GRIN1GRIN2A | |
| SCHEMBL5727444 | 0.82 | CHRM2 (0.53) | MPOCHRM2GRIN1GRIN2ABCHE | |
| SCHEMBL13330463 | 0.82 | ALDH1A1 (0.63) | HTR2AHTR2CGAAALDH1A1CHRM2 | |
| SCHEMBL11711401 | 0.82 | BCHE (0.66) | HTR2AHTR2CGAAMPOBCHE | |
| SCHEMBL8607958 | 0.82 | CHRM2 (0.62) | HTR2AHTR2CMPOCHRM2GRIN1 | |
| SCHEMBL30166692 | 0.82 | BCHE (0.66) | HTR2AHTR2CGAAMPOBCHE | |
| Hydrochloric Acid SCHEMBL4354687 | 0.81 | CHRM2 (0.73) | GAAALDH1A1CHRM2GRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230181494-A1 | COMPOSITIONS AND METHODS OF USE OF GAMMA-KETOALDEHYDE SCAVENGERS FOR TREATING, PREVENTING OR IMPROVING NONALCOHOLIC FATTY LIVER DISEASE (NAFLD), NASH, ALD OR CONDITIONS RELATED TO THE LIVER | MTI BIOTECH, INC. | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230181494-A1 | COMPOSITIONS AND METHODS OF USE OF GAMMA-KETOALDEHYDE SCAVENGERS FOR TREATING, PREVENTING OR IMPROVING NONALCOHOLIC FATTY LIVER DISEASE (NAFLD), NASH, ALD OR CONDITIONS RELATED TO THE LIVER | CPT1A, AKR7A2, FABP1 | HTR2A 3310/4885HTR2C 3773/4885ALOX5 169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.