Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | HTR2A | P28223 | 1/20 | 0.60 |
| ▸ | HTR2C | P28335 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | BCHE | P06276 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.53 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.53 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.53 |
| ▸ | ACHE | P22303 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3965713 | 0.90 | ALDH1A1 (0.60) | ALDH1A1HTR2AHTR2CCYP3A4CYP2D6 | |
| SCHEMBL3962959 | 0.88 | CHRM2 (0.63) | ALDH1A1CYP3A4CYP2D6BCHEKMT2A | |
| SCHEMBL7000552 | 0.88 | KDM4E (0.69) | ALDH1A1HTR2AHTR2CKDM4EL3MBTL1 | |
| SCHEMBL31711441 | 0.86 | KDM4E (0.60) | ALDH1A1HTR2AHTR2CKDM4EL3MBTL1 | |
| SCHEMBL8138468 | 0.84 | CHRM2 (0.72) | ALDH1A1CYP3A4CYP2D6GAABCHE | |
| SCHEMBL5727444 | 0.83 | CHRM2 (0.53) | CYP3A4CYP2D6BCHEKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL4354687 | 0.83 | CHRM2 (0.73) | ALDH1A1CYP3A4CYP2D6GAABCHE | |
| Hydrochloric Acid SCHEMBL9351001 | 0.83 | CHRM2 (0.73) | ALDH1A1CYP3A4CYP2D6GAABCHE | |
| SCHEMBL25609403 | 0.82 | HTR2A (0.61) | ALDH1A1HTR2AHTR2CCYP3A4CYP2D6 | |
| SCHEMBL6136209 | 0.79 | ALDH1A1 (0.55) | ALDH1A1HTR2AHTR2CKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8642801-B2 | Methods and compositions for treating amyloid-related diseases | BHI LIMITED PARTNERSHIP (CA) | 2014-02-04 | — | — | US | disclosed |
| US-20100113591-A1 | METHODS AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES | BELLUS HEALTH (INTERNATIONAL) LIMITED (CH) | 2010-05-06 | — | — | US | disclosed |
| US-7504391-B2 | Selective D1/D5 receptor antagonists for the treatment of obesity and CNS disorders | SCHERING CORPORATION (US) | 2009-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113591-A1 | METHODS AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES | APP, PSEN1, PSEN2 | ALDH1A1 2989/4885HTR2A 2007/4885HTR2C 3329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.