Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | PRF1 | P14222 | 2/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP9X | Q93008 | 1/20 | 0.36 |
| ▸ | USP24 | Q9UPU5 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18220167 | 0.89 | ALDH1A1 (0.48) | LMNAALDH1A1KMT2AMAPTMAPK1 | |
| SCHEMBL17120684 | 0.89 | LMNA (0.44) | LMNAALDH1A1KMT2AMAPTMAPK1 | |
| SCHEMBL25609499 | 0.87 | KMT2A (0.41) | LMNAALDH1A1KMT2AMAPTMAPK1 | |
| SCHEMBL18220274 | 0.87 | KMT2A (0.45) | LMNAALDH1A1KMT2AMAPTMAPK1 | |
| SCHEMBL17120832 | 0.87 | APP (0.43) | LMNAALDH1A1KMT2AMAPTMAPK1 | |
| SCHEMBL25609471 | 0.85 | ALDH1A1 (0.42) | LMNAALDH1A1KMT2AMAPTMAPK1 | |
| SCHEMBL18221569 | 0.84 | LMNA (0.41) | LMNAALDH1A1KMT2AMAPTMAPK1 | |
| SCHEMBL25611400 | 0.84 | LMNA (0.41) | LMNAALDH1A1KMT2AMAPTMAPK1 | |
| SCHEMBL24075923 | 0.84 | LMNA (0.41) | LMNAALDH1A1KMT2AMAPTMAPK1 | |
| SCHEMBL25611396 | 0.84 | LMNA (0.41) | LMNAALDH1A1KMT2AMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3119761-B1 | AMYLOID TARGETING AGENTS AND METHODS OF USING THE SAME | AMYDIS DIAGNOSTICS INC (US) | 2023-06-07 | — | — | EP | disclosed |