SCHEMBL2561071

SCHEMBL2561071

CCCCCNC(=O)C(C)Oc1ccccc1C=O

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 3/20 0.47
MAPT P10636 3/20 0.47
LMNA P02545 2/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
GAA P10253 1/20 0.46
ALDH1A1 P00352 2/20 0.44
ZDHHC2 Q9UIJ5 1/20 0.43
PKM P14618 1/20 0.43
EGFR P00533 1/20 0.40
EPHX1 P07099 2/20 0.40
HTT P42858 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29950819 0.96 GAA (0.47) NAAAMAPTLMNAMEN1KMT2A
SCHEMBL2558613 0.91 PKM (0.46) MAPTLMNAMEN1KMT2AL3MBTL1
SCHEMBL2555096 0.86 GAA (0.51) MAPTLMNAMEN1KMT2AL3MBTL1
SCHEMBL29952275 0.85 SMN1; SMN2 (0.52) LMNAKMT2AGAAALDH1A1PKM
SCHEMBL15330180 0.85 MAPT (0.50) MAPTLMNAMEN1KMT2AL3MBTL1
SCHEMBL2557903 0.84 HPGD (0.56) MAPTLMNAMEN1KMT2AL3MBTL1
SCHEMBL15331066 0.82 PTGDR2 (0.43) MAPTLMNAMEN1KMT2AGAA
SCHEMBL29955443 0.80 SMN1; SMN2 (0.56) MAPTLMNAMEN1KMT2AL3MBTL1
SCHEMBL2556326 0.80 PTGDR2 (0.44) MAPTLMNAMEN1KMT2AL3MBTL1
SCHEMBL2558716 0.80 POLB (0.41) LMNAKMT2AGAAALDH1A1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
US-11225655-B2 Bi-functional complexes and methods for making and using such complexes NUEVOLUTION A/S (DK) 2022-01-18 US disclosed
EP-3540059-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES Nuevolution A/S (DK) 2019-09-18 EP disclosed
EP-2558577-B1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION AS (DK) 2018-12-12 EP disclosed
US-20130281324-A1 BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2013-10-24 US disclosed
EP-2558577-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES Nuevolution A/S (DK) 2013-02-20 EP disclosed
WO-2011127933-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2011-10-20 WO disclosed