Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NAAA | Q02083 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2561071 | 0.96 | NAAA (0.47) | GAALMNAMAPTKMT2AMEN1 | |
| SCHEMBL2558613 | 0.92 | PKM (0.46) | GAALMNAMAPTKMT2AMEN1 | |
| SCHEMBL2555096 | 0.88 | GAA (0.51) | GAALMNAMAPTKMT2AMEN1 | |
| SCHEMBL29952275 | 0.87 | SMN1; SMN2 (0.52) | GAALMNAKMT2APKMHTT | |
| SCHEMBL15330180 | 0.86 | MAPT (0.50) | GAALMNAMAPTKMT2AMEN1 | |
| SCHEMBL2557903 | 0.85 | HPGD (0.56) | GAALMNAMAPTKMT2AMEN1 | |
| SCHEMBL29955443 | 0.83 | SMN1; SMN2 (0.56) | GAALMNAMAPTKMT2AMEN1 | |
| SCHEMBL15331066 | 0.83 | PTGDR2 (0.43) | GAALMNAMAPTKMT2AMEN1 | |
| SCHEMBL2555960 | 0.82 | POLB (0.44) | GAALMNAL3MBTL1TSHRHTT | |
| SCHEMBL29953502 | 0.81 | MEN1 (0.47) | GAALMNAMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |