Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TK1 | P04183 | 1/20 | 0.36 |
| ▸ | DUT | P33316 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25611288 | 0.87 | POLB (0.84) | POLBHSD17B10ALDH1A1TK1DUT | |
| SCHEMBL25611388 | 0.84 | POLB (0.61) | POLBHSD17B10ALDH1A1TK1DUT | |
| SCHEMBL25605504 | 0.83 | POLB (0.46) | POLBHSD17B10ALDH1A1DUTLMNA | |
| SCHEMBL20052005 | 0.81 | POLB (0.72) | POLBHSD17B10ALDH1A1TK1DUT | |
| SCHEMBL23710595 | 0.81 | POLB (0.85) | POLBHSD17B10ALDH1A1TK1DUT | |
| SCHEMBL13443477 | 0.79 | POLB (0.79) | POLBHSD17B10ALDH1A1TK1DUT | |
| SCHEMBL25583967 | 0.79 | POLB (0.69) | POLBHSD17B10ALDH1A1TK1DUT | |
| SCHEMBL19221806 | 0.79 | POLB (0.63) | POLBHSD17B10ALDH1A1TK1DUT | |
| SCHEMBL23710643 | 0.78 | POLB (0.68) | POLBHSD17B10ALDH1A1TK1DUT | |
| SCHEMBL14867637 | 0.78 | POLB (0.68) | POLBHSD17B10ALDH1A1TK1DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159929-A1 | MODIFIED SHORT INTERFERING NUCLEIC ACID (siNA) MOLECULES AND USES THEREOF | ALIGOS THERAPEUTICS, INC. | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159929-A1 | MODIFIED SHORT INTERFERING NUCLEIC ACID (siNA) MOLECULES AND USES THEREOF | SNRPA, SNRPA1, NSUN2 | POLB 57/4885HSD17B10 4429/4885ALDH1A1 3817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.