Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 9/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 8/20 | 0.45 |
| ▸ | CA1 | P00915 | 7/20 | 0.45 |
| ▸ | CA9 | Q16790 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 2/20 | 0.42 |
| ▸ | CA5A | P35218 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29324991 | 1.00 | CYP2D6 (0.57) | CYP2D6THRBHSD17B10CA2LMNA | |
| SCHEMBL16169885 | 1.00 | CYP2D6 (0.57) | CYP2D6THRBHSD17B10CA2LMNA | |
| SCHEMBL15444981 | 1.00 | CYP2D6 (0.57) | CYP2D6THRBHSD17B10CA2LMNA | |
| SCHEMBL15102101 | 1.00 | CYP2D6 (0.57) | CYP2D6THRBHSD17B10CA2LMNA | |
| SCHEMBL10819141 | 1.00 | CYP2D6 (0.57) | CYP2D6THRBHSD17B10CA2LMNA | |
| SCHEMBL19396308 | 1.00 | CYP2D6 (0.57) | CYP2D6THRBHSD17B10CA2LMNA | |
| SCHEMBL9925403 | 1.00 | CYP2D6 (0.57) | CYP2D6THRBHSD17B10CA2LMNA | |
| SCHEMBL15444975 | 1.00 | CYP2D6 (0.57) | CYP2D6THRBHSD17B10CA2LMNA | |
| SCHEMBL14429311 | 0.95 | CYP2D6 (0.56) | CYP2D6THRBHSD17B10CA2LMNA | |
| SCHEMBL17521933 | 0.93 | CYP2D6 (0.51) | CYP2D6THRBHSD17B10CA2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230212158-A1 | SMALL MOLECULE INHIBITORS OF GALECTIN-3 | BRISTOL MYERS SQUIBB CO (US) | 2023-07-06 | — | — | US | disclosed |
| US-20230192672-A1 | SMALL MOLECULE INHIBITORS OF GALECTIN-3 | BRISTOL MYERS SQUIBB (US) | 2023-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230212158-A1 | SMALL MOLECULE INHIBITORS OF GALECTIN-3 | LGALS3, LGALS1, LGALS3BP | CYP2D6 4255/4885THRB 2469/4885HSD17B10 3531/4885 |
| US-20230192672-A1 | SMALL MOLECULE INHIBITORS OF GALECTIN-3 | LGALS3, LGALS3BP, LGALS1 | CYP2D6 3826/4885THRB 2411/4885HSD17B10 3276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.