Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 4/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | CKS1B | P61024 | 1/20 | 0.39 |
| ▸ | SKP1 | P63208 | 1/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12794288 | 0.90 | CTSK (0.52) | CTSKDRD2KDM1AMAOBOPRM1 | |
| SCHEMBL12794285 | 0.90 | CTSK (0.52) | CTSKDRD2KDM1AMAOBOPRM1 | |
| SCHEMBL8863228 | 0.86 | CTSK (0.55) | CTSKDRD2KDM1AMAOBBTK | |
| SCHEMBL12355111 | 0.85 | CTSK (0.48) | CTSKDRD2KDM1AMAOBOPRM1 | |
| SCHEMBL12731380 | 0.85 | CTSK (0.48) | CTSKDRD2KDM1AMAOBOPRM1 | |
| SCHEMBL3208307 | 0.84 | CTSK (0.50) | CTSKDRD2KDM1AMAOBOPRM1 | |
| SCHEMBL1543136 | 0.84 | CTSK (0.50) | CTSKDRD2KDM1AMAOBOPRM1 | |
| SCHEMBL3545803 | 0.84 | CTSK (0.50) | CTSKDRD2KDM1AMAOBOPRM1 | |
| SCHEMBL20438259 | 0.84 | CTSK (0.50) | CTSKDRD2KDM1AMAOBOPRM1 | |
| SCHEMBL4157853 | 0.84 | CTSK (0.50) | CTSKDRD2KDM1AMAOBOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104195-A1 | PREPARATION METHOD FOR ISOTHIAZOLO[5,4-D]PYRIMIDINE IRAK4 INHIBITOR | 正大天晴药业集团股份有限公司 | 2023-06-15 | — | — | WO | disclosed |