Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.55 |
| ▸ | BTK | Q06187 | 1/20 | 0.48 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CKS1B | P61024 | 1/20 | 0.46 |
| ▸ | SKP1 | P63208 | 1/20 | 0.46 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1307245 | 0.91 | CTSK (0.59) | CTSKBTKKCNA3CA1CA2 | |
| SCHEMBL14206912 | 0.91 | CTSK (0.59) | CTSKBTKKCNA3CA1CA2 | |
| SCHEMBL6826860 | 0.91 | CTSK (0.59) | CTSKBTKKCNA3CA1CA2 | |
| SCHEMBL25612634 | 0.86 | CTSK (0.45) | CTSKBTKKCNA3CA1CA2 | |
| SCHEMBL29107097 | 0.84 | CTSK (0.52) | CTSKBTKKCNA3CA1CA2 | |
| SCHEMBL21566717 | 0.83 | CTSK (0.50) | CTSKBTKKCNA3CA1CA2 | |
| SCHEMBL16162710 | 0.83 | CA1 (0.60) | CTSKBTKCA1CA2HSD11B1 | |
| SCHEMBL24068416 | 0.81 | CTSK (0.59) | CTSKBTKKCNA3CA1CA2 | |
| SCHEMBL359203 | 0.81 | CTSK (0.59) | CTSKBTKKCNA3CA1CA2 | |
| SCHEMBL10343938 | 0.80 | BTK (0.61) | CTSKBTKCA1CA2HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3992191-A1 | IMIDAZO[4,5-C]QUINOLINE COMPOUNDS AND THEIR USE AS ATM KINASE INHIBITORS | Deutsches Krebsforschungszentrum (DE) | 2022-05-04 | — | — | EP | disclosed |
| US-7268150-B2 | 2-cyano-4-fluoropyrrolidine derivative or its salt | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 2007-09-11 | — | — | US | disclosed |
| CN-1312127-C | 2-cyano-4-fluoropyrrolidine derivative or its salt | YAMANOUCHI PHARMA CO LTD (JP) | 2007-04-25 | — | — | CN | disclosed |
| CN-1665785-A | 2-cyano-4-fluoropyrrolidine derivative or its salt | YAMANOUCHI PHARMA CO LTD (JP) | 2005-09-07 | — | — | CN | disclosed |
| US-5663139-A | VIRICIDE OLIGOPEPTIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-09-02 | — | — | US | disclosed |