Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | MAP4K1 | Q92918 | 2/20 | 0.33 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.33 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.33 |
| ▸ | SGK1 | O00141 | 1/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25627364 | 0.87 | MAP3K7 (0.33) | CNR2MAP4K1MAP3K7TAB1SGK1 | |
| SCHEMBL25613041 | 0.85 | ADRA2A (0.33) | ADRA1DADRA1AADRA1BADRA2AADRA2C | |
| SCHEMBL25613048 | 0.82 | TSHR (0.35) | ADRA1DADRA1AADRA1BADRA2AADRA2C | |
| SCHEMBL25613042 | 0.82 | MAP3K7 (0.37) | MAP3K7TAB1MEN1KMT2ALMNA | |
| SCHEMBL25613175 | 0.80 | ADRA2A (0.37) | ADRA1DADRA1AADRA1BADRA2AADRA2C | |
| SCHEMBL25613040 | 0.80 | MAPK1 (0.31) | MAP3K7TAB1ADRA1DADRA1AADRA1B | |
| SCHEMBL25613038 | 0.77 | CDK1 (0.32) | ADRA1DADRA1AADRA1BADRA2AADRA2C | |
| SCHEMBL25613035 | 0.76 | ULK1 (0.39) | CNR2MAP4K1MEN1KMT2ACYP1A2 | |
| SCHEMBL25613168 | 0.75 | ADRA2A (0.33) | ADRA1DADRA1AADRA1BADRA2AADRA2C | |
| SCHEMBL25613023 | 0.74 | ADRA2A (0.31) | ADRA1DADRA1AADRA1BADRA2AADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159527-A1 | COMPOUNDS AS BCL-2 INHIBITORS | FOCHON BIOSCIENCES, LTD. (CN) | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159527-A1 | COMPOUNDS AS BCL-2 INHIBITORS | BCL2, BCL2L2, BCL2L1 | CNR2 3383/4885MAP4K1 3329/4885MAP3K7 2282/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.