Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | WNT1 | P04628 | 6/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.40 |
| ▸ | SCD | O00767 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.38 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.38 |
| ▸ | POLQ | O75417 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25612757 | 0.87 | CSNK2A2 (0.42) | PDE10AKDRWNT1DYRK1ACSNK2A2 | |
| SCHEMBL25612756 | 0.75 | DYRK1A (0.66) | WNT1DYRK1AGSK3B | |
| SCHEMBL25605965 | 0.74 | XDH (0.42) | PDE10AKDRCSNK2A2CSNK2A1 | |
| SCHEMBL25613351 | 0.74 | DYRK1A (0.50) | KDRWNT1DYRK1AGSK3B | |
| SCHEMBL25612688 | 0.74 | CSNK2A2 (0.42) | PDE10AKDRWNT1DYRK1ACSNK2A2 | |
| SCHEMBL25613752 | 0.73 | GSK3B (0.50) | WNT1DYRK1AKDM4ELMNARAB9A | |
| SCHEMBL31271677 | 0.72 | GSK3B (0.52) | WNT1DYRK1AGSK3B | |
| SCHEMBL25613237 | 0.72 | GSK3B (0.52) | WNT1DYRK1AGSK3B | |
| SCHEMBL25613753 | 0.72 | GSK3B (0.40) | WNT1DYRK1ALMNAKMT2AGSK3B | |
| SCHEMBL25613678 | 0.72 | GSK3B (0.54) | WNT1DYRK1ARAB9AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107714-A2 | METHODS FOR TREATING NEUROLOGICAL DISORDERS | PROTHENA BIOSCIENCES LIMITED (IE) | 2023-06-15 | — | — | WO | disclosed |