Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT1 | P04628 | 6/20 | 0.49 |
| ▸ | GSK3B | P49841 | 6/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 8/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25613237 | 0.96 | GSK3B (0.52) | WNT1GSK3BDYRK1ACNR2HDAC3 | |
| SCHEMBL31271677 | 0.96 | GSK3B (0.52) | WNT1GSK3BDYRK1ACNR2HDAC3 | |
| SCHEMBL25612756 | 0.84 | DYRK1A (0.66) | WNT1GSK3BDYRK1AMKNK1ABL1 | |
| SCHEMBL25614115 | 0.82 | GSK3B (0.54) | WNT1GSK3BDYRK1ACNR2HDAC3 | |
| SCHEMBL25613678 | 0.82 | GSK3B (0.54) | WNT1GSK3BDYRK1AMKNK1ABL1 | |
| SCHEMBL25613752 | 0.82 | GSK3B (0.50) | WNT1GSK3BDYRK1ACNR2SMN1; SMN2 | |
| SCHEMBL25613668 | 0.82 | GSK3B (0.43) | WNT1GSK3BDYRK1ACNR2HDAC3 | |
| SCHEMBL25611613 | 0.82 | WNT1 (0.48) | WNT1GSK3BDYRK1ACNR2HDAC3 | |
| SCHEMBL31271858 | 0.81 | GSK3B (0.48) | WNT1GSK3BDYRK1AMKNK1ABL1 | |
| SCHEMBL25609006 | 0.81 | GSK3B (0.48) | WNT1GSK3BDYRK1AMKNK1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107714-A2 | METHODS FOR TREATING NEUROLOGICAL DISORDERS | PROTHENA BIOSCIENCES LIMITED (IE) | 2023-06-15 | — | — | WO | disclosed |