Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 8/20 | 0.50 |
| ▸ | CHRNA3 | P32297 | 8/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14562446 | 0.87 | ATM (0.51) | CHRNB4CHRNA3ATMCHRNB2CHRNA4 | |
| SCHEMBL31125777 | 0.82 | CHRNB4 (0.49) | CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL25614205 | 0.81 | CHRNB2 (0.55) | CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL3939071 | 0.79 | ATM (0.53) | CHRNB4CHRNA3ATMCHRNB2CHRNA4 | |
| SCHEMBL14562451 | 0.79 | ATM (0.53) | CHRNB4CHRNA3ATMCHRNB2CHRNA4 | |
| SCHEMBL27961107 | 0.78 | ATM (0.44) | CHRNB4CHRNA3ATMCHRNB2CHRNA4 | |
| SCHEMBL27961108 | 0.78 | ATM (0.44) | CHRNB4CHRNA3ATMCHRNB2CHRNA4 | |
| SCHEMBL2953402 | 0.77 | ALDH1A1 (0.56) | ATM | |
| SCHEMBL31705336 | 0.77 | CHRNB2 (0.61) | ATMCHRNB2CHRNA4CYP11B1CYP11B2 | |
| SCHEMBL20604746 | 0.77 | CHRNB2 (0.61) | ATMCHRNB2CHRNA4CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104209-A1 | METTL3 INHIBITOR COMPOUND | 上海昂阔医药有限公司 | 2023-06-15 | — | — | WO | disclosed |