Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.45 |
| ▸ | CLK2 | P49760 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20897510 | 0.80 | ALDH1A1 (0.55) | CRBNDDB1NPC1RAB9AKMT2A | |
| SCHEMBL3939071 | 0.78 | ATM (0.53) | ATMCYP11B2CYP11B1CHRNB2CHRNA4 | |
| SCHEMBL31368772 | 0.78 | CHRNB2 (0.45) | ATMCYP11B2CYP11B1CHRNB2CHRNA4 | |
| SCHEMBL30686532 | 0.78 | CHRNB2 (0.45) | ATMCYP11B2CYP11B1CHRNB2CHRNA4 | |
| SCHEMBL475674 | 0.76 | ALDH1A1 (0.43) | NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL664858 | 0.76 | ATM (0.50) | ATMCYP11B2CYP11B1NPC1RAB9A | |
| SCHEMBL31705336 | 0.76 | CHRNB2 (0.61) | ATMCYP11B2CYP11B1CHRNB2CHRNA4 | |
| SCHEMBL20604746 | 0.76 | CHRNB2 (0.61) | ATMCYP11B2CYP11B1CHRNB2CHRNA4 | |
| SCHEMBL30686495 | 0.76 | ATM (0.42) | ATMCYP11B2CYP11B1CHRNB2CHRNA4 | |
| SCHEMBL14562451 | 0.75 | ATM (0.53) | ATMCYP11B2CYP11B1CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104209-A1 | METTL3 INHIBITOR COMPOUND | 上海昂阔医药有限公司 | 2023-06-15 | — | — | WO | disclosed |